Pharmaceutical Biotechnology. Guide to Practical Exercises. Study Guide

The study manual provides information on modern methods of obtaining medical drugs in the conditions of industrial biopharmaceutical production. The most attention is paid to the biotechnological aspects of antibiotics. Methods are highlighted from the soil of microorganisms - antibiotic producers from the soil, their identification by culture and morphological features and storage of producers microorganisms. Microbiological methods for determining the sensitivity and concentration of antibiotics are presented. Information about the industrial preparations of various pharmacological groups (vitamins and coenzymes, amino acids, steroid hormones, etc) with biotechnology are given. Examples of obtaining recombinant structures in laboratory conditions are shown. The technological techniques used to assess the quality of finished vaccines are considered.
In the textbook, all the necessary software materials for passing the course of pharmaceutical biotechnology by students of medical universities are given.
To facilitate the assimilation of the material, the Handbook includes a dictionary-directory with comments.
Tutorial is intended to students, interns, graduate students and teachers of medical universities