Mitochondrial diseases. A guide for doctors.

Mitochondrial diseases are a heterogeneous group of inherited diseases in which the structure and functions of the mitochondrial respiratory chain are disrupted. Due to the wide clinical polymorphism, dual genetic control of the mitochondrial respiratory chain, this group of diseases poses many difficulties in clinical and laboratory diagnostics. The book describes the main clinical manifestations, features of functional and laboratory diagnostics, medical-genetic counseling, and modern approaches to the therapy of this group of diseases. The authors have summarized the literature data and their extensive experience in clinical-laboratory diagnostics of mitochondrial diseases. The publication is intended for neurologists, geneticists, pediatricians, ophthalmologists, physicians in related specialties such as endocrinologists, cardiologists, audiologists, and other specialists, as well as residents and medical students.