Magnesium + B6, 60 tablets of 300 mg each

Magnesium is an essential element found in all tissues of the body and is necessary for the normal functioning of cells, participating in most metabolic reactions. In particular, it is involved in regulating the transmission of nerve impulses and muscle contraction. The body obtains magnesium through food. A deficiency of magnesium in the body can occur with dietary irregularities or increased magnesium needs (during physical and mental stress, pregnancy, or the use of diuretics). Pyridoxine (vitamin B6) is involved in many metabolic processes and in regulating the nervous system metabolism. Vitamin B6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells. The magnesium content in serum: - from 12 to 17 mg/l (0.5 – 0.7 mmol/l) indicates moderate magnesium deficiency, - below 12 mg/l (0.5 mmol/l) indicates severe magnesium deficiency. Pharmacokinetics The absorption of magnesium in the gastrointestinal tract is not more than 50% of the orally administered dose. 99% of magnesium in the body is found inside cells. Approximately 2/3 of intracellular magnesium is distributed in bone tissue, while the other 1/3 is found in smooth and striated muscle tissue. Magnesium is primarily excreted in the urine. At least 1/3 of the magnesium dose taken is excreted in the urine. Indications Established magnesium deficiency, isolated or associated with other deficiency states, accompanied by symptoms such as increased irritability, minor sleep disturbances, gastrointestinal spasms or palpitations, increased fatigue, muscle pain and spasms, and tingling sensations.